NAD+ Therapy - Anti-Aging & Cellular Regeneration

Simon Lee, MD -  - Aesthetics

Simon Med Spa

Simon Lee, MD

Aesthetics located in Milpitas, CA & Burlingame, CA

NAD+ Therapy - Anti-Aging & Cellular Regeneration

NAD+ Therapy - Anti-Aging & Cellular Regeneration

NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme present in every cell, essential for energy production, DNA repair, and cellular longevity. With age, NAD+ levels decline by up to 50% by middle age, contributing to aging and metabolic dysfunction. NAD+ therapy delivers direct intravenous infusion or oral/sublingual formulations to restore youthful cellular function.

 

Key Benefits

✔ Boosts Cellular Energy: Enhances mitochondrial ATP production

✔ DNA Repair Activation: Supports sirtuin proteins (SIRT1-7) for genomic stability

✔ Anti-Aging Effects: Shown to extend lifespan in preclinical studies

✔ Neuroprotection: May improve cognitive function and reduce neurodegeneration risk

 

Science Behind NAD+

1. Mitochondrial Fuel: Critical for electron transport chain (ETT) in ATP synthesis

2. Sirtuin Activation: Regulates longevity pathways (e.g., FOXO, p53)

3. Metabolic Support: Improves insulin sensitivity and lipid metabolism

 

Clinical Applications

▶ Anti-Aging: Skin rejuvenation, muscle preservation

▶ Neurological: Alzheimer’s/Parkinson’s support (investigational)

▶ Metabolic: Obesity, type 2 diabetes adjunct therapy

▶ Addiction Recovery: Reduces withdrawal symptoms (FDA-approved for alcohol dependence)

 

Delivery Methods

▸ IV Infusion: 100-500mg doses (30-90 min sessions) for immediate bioavailability

▸ Oral/Sublingual: NR (Nicotinamide Riboside) or NMN supplements

▸ Intramuscular: Lower-dose maintenance therapy

 

Treatment Protocol

• Initial Phase: 4-6 IV sessions over 2-3 weeks

• Maintenance: Monthly infusions or daily NR/NMN (250-1000mg)

 

Safety:

• Generally well-tolerated

• Mild flushing/nausea possible during IV administration